Presentation Slides - The Importance of Good Experimental Design for Extractable and Leachable Studies

Blog - AMS Science Lead Mike Ludlow explains the importance of good experimental design for extractable and leachable studies.

10 November 2022
A step-by-step guide to developing a robust assay in bioanalysis using LC-MS/MS

Blog - Read our guide ‘A step-by-step guide to developing a robust assay in bioanalysis using LC-MS/MS’ to learn about our proven approach to developing industry-leading LC-MS/MS bioassays.

22 September 2022
CRO Alliance Pharma’s Executive Team Grows by Four, Supporting Bioanalytical and CMC Testing Expansions

News - Alliance Pharma (Alliance), a global leader in bioanalytical, DMPK and CMC testing services in the pharmaceutical and biopharmaceutical industry, has grown their leadership team by four, bringing onboard a new Chief Operating Officer (COO), Chief Commercial Officer (CCO), Chief Financial Officer (CFO), and Chief People Officer (CPO). These leaders will support continued global expansion, which includes Alliance’s recent acquisition of U.K.-based Drug Development Solutions (DDS) from LGC and new bioanalytical laboratory opening in Australia in November.

21 September 2022
Cocrystal - Motivation and Theory - Solid Form Screening

Blog - Sponsors may require a cocrystal screen for a number of reasons, or a combination of these, dissolution rate/solubility, crystallinity, novelty, hydration issues, other processability and stability.

21 September 2022
Crystallisation and Screening Theory - Solid Form Screening

Blog - Crystals are distinguished from amorphous solids by possessing both short and long range regular structure, minimal repeating units within this matrix are termed unit cells.

15 September 2022
Salt Screening - Motivation and Theory - Solid Form Screening

Blog - Sponsors may require a salt screen for a number of reasons, or a combination of these: Solubility, Stability, Crystallinity, Novelty, Other processability.

14 September 2022
What makes a good LC-MS/MS bioassay?

Blog - What makes a good LC-MS/MS bioassay? When selecting your LC-MS/MS method approach it is worth doing your homework. Pick an assay format that is best suited to your compound and consider factors such as matrix type, analyte structure, choice and availability of reagents, and the sensitivity and specificity you need.

01 September 2022
Polymorph Screening - Motivation and Theory - Solid Form Screening

Blog - It is unusual for a sponsor to require a polymorph screen before investigating salts and cocrystals first. All crystalline materials, whether parent API, salt or cocrystal may exist in multiple polymorphic forms usually identified by the Roman numerals I, II, III, IV etc.

12 August 2022
U.S. Alliance Pharma Expands Early Phase Bioanalytical Services Into Australia

News - Alliance Pharma (Alliance), a U.S. leader in small and large molecule bioanalytical services in the pharmaceutical and biopharmaceutical industry, today closed on the purchase of Drug Development Solutions Business (DDS), a UK-based bioanalytical and material science testing contract research organization (CRO), from LGC. Ampersand Capital Partners, a healthcare private equity firm and KKR & Co. Inc. (KKR) (NYSE:KKR) a leading global investment firm, will become equal shareholders in the combined company. This transaction expands bioanalytical, analytical material testing and laboratory capabilities internationally for the biopharma and pharma industry, including areas of cell and gene therapy, next-generation biologics, material sciences and protein characterization.

11 August 2022
A method to measure anti-vaccine antibodies

Blog - An antibody assay was required to detect and quantify IgGs produced against a vaccine. This was required to measure the efficacy and reliability of the vaccine.

15 July 2022