April 2021

The benefits of HRMS compared to QqQ

The implementation of HRMS in bioanalytical workflows can offer additional levels of selectivity, not attainable with traditional QqQ workflows. A clear benefit of this additional instrumental selectivity is the ability to dial back on the extent and complexity of physical clean-up procedures applied to our samples, realising efficiency gains in our workflows.

This infographic explores top tips to prolong periods between instrument cleans, compare cleaning times for QqQ and QToF platforms and provide an assessment of robustness, with a focus on sensitivity level and mass accuracy. Finally, it presents common trends to be aware of when the QToF platform has become contaminated and requires cleaning.